Kairat vs Club Brugge The hosts will look to frustrate early, but Brugge’s European experience should tell over 90 minutes. Prediction: Kairat 0–2 Club Brugge Best Bet: Club Brugge Win + Under 3.5 Goals Bodo/Glimt vs Manchester City A tricky away trip inside the Arctic Circle, but City’s depth and control should overcome the conditions. Prediction: Bodo/Glimt 1–3 Manchester City Best Bet: City Win + Over 2.5 Goals Villarreal vs Ajax Two technical sides meet in Spain. Expe

Espanyol vs Girona Espanyol host Girona in what promises to be a lively Catalan derby. Girona have exceeded expectations this season and look far more cohesive going forward, while Espanyol continue to struggle defensively. Prediction: Espanyol 1-2 Girona Best Bet: Girona win or draw + BTTS Real Madrid vs Levante Real Madrid should have little trouble at the Bernabéu against Levante. With the title race heating up, anything less than three points would be a major surprise.

Pisa vs Atalanta Pisa welcome Atalanta knowing they face one of the most dangerous attacking sides in the league. Atalanta’s intensity and depth should overwhelm the hosts, especially if the game opens up early. Prediction: Pisa 1-3 Atalanta Best Bet: Atalanta win + Over 2.5 goals Udinese vs Inter Inter travel to Udine looking to maintain pressure at the top of the table. Udinese can be stubborn at home, but Inter’s control and finishing quality should see them through. Pre

Manchester United vs Manchester City The Manchester Derby sees United host City at Old Trafford. Under new manager Michael Carrick, United will hope to fend off a resilient City side looking to renew momentum in the hopes of closing the gap with Arsenal. The game of the week will be the early kick-off on Saturday, opening the show for Matchweek 22. Prediction: United 1-2 City Best Bet: Haaland to score + Cherki to assist + Over 3 cards Sunderland vs Crystal Palace Hampere

Como vs Bologna Como continue to scrap for points at home, but Bologna’s organisation and pressing should give them control over the midfield battle. Prediction: Como 1-2 Bologna Best Bet: Bologna win or draw + BTTS Udinese vs Pisa Udinese’s physicality and experience at this level should overwhelm a Pisa side that often struggles away from home. Prediction: Udinese 2-0 Pisa Best Bet: Udinese win + Clean sheet Roma vs Sassuolo Roma will look to dominate possession and t

Getafe vs Real Sociedad Getafe remain difficult to break down at home, but Sociedad’s superior technical quality and control in midfield should eventually show across 90 minutes. Prediction: Getafe 0-1 Real Sociedad Best Bet: Real Sociedad win + Under 2.5 goals Oviedo vs Real Betis Oviedo’s return to the top flight has been spirited, but Betis arrive with more composure and attacking balance, especially in wide areas. Prediction: Oviedo 1-2 Real Betis Best Bet: Betis win

Eintracht Frankfurt vs Borussia Dortmund Friday night football sees Frankfurt host Dortmund in what should be an open, high-tempo encounter. Dortmund’s attacking quality gives them the edge, but Frankfurt are always dangerous at home under the lights. Prediction: Frankfurt 1-2 Dortmund Best Bet: BTTS + Over 2.5 goals Heidenheim vs Köln A relegation six-pointer where nerves will be high. Heidenheim’s home form could prove decisive against a Köln side struggling for goals on

Pisa vs Como A relegation six-pointer opens the matchweek as Pisa host Como. Both sides are struggling for consistency, and this fixture feels like a must-not-lose rather than a must-win. Prediction: Pisa 1-1 Como Best Bet: BTTS + Over 3 cards Lecce vs Roma Roma travel south knowing three points are essential if they are to stay in touch with the European places. Lecce are stubborn at home but lack the attacking quality to trouble Roma consistently. Prediction: Lecce 0-2

Clicking on the “Best Bet” text will redirect you to Midnite , where new customers can receive £30 in free bet credits when signing up. T&Cs apply. West Ham United vs Nottingham Forest The Irons host Forest for the sole game on Tuesday, in what is expected to be a tight encounter. West Ham are fresh off a thrashing from last-place Wolves, a damning indictment of a terrible season which sees them firmly in the relegation zone. Prediction: West Ham 0-2 Forest Best Bet: Fores

Aston Villa vs Nottingham Forest A Midlands derby kicks off the weekend as Aston Villa host old rivals Forest. Villa are pushing hard for a top-four finish, while Forest arrive focused purely on survival. The gulf in quality should show, especially at Villa Park. Prediction: Aston Villa 3-1 Nottingham Forest Best Bet: Rogers to score + Over 3 goals + BTTS Brighton vs Burnley Two out-of-form sides meet on the south coast. Brighton have slid alarmingly down the table after a

Monaco vs Lorient Monaco remain strong at home and should have too much quality for a Lorient side that struggles away from home. Prediction: Monaco 2-0 Lorient Best bet: Monaco to win & under 3.5 goals PSG vs LOSC Lille A heavyweight clash at the Parc des Princes. Lille can cause problems, but PSG’s depth and firepower should prevail. Prediction: PSG 2-1 Lille Best bet: PSG to win & both teams to score Lens vs Auxerre Lens’ high intensity and home crowd should overwhelm

Rayo Vallecano vs Getafe A classic Madrid derby with plenty of physical battles. Rayo’s intensity at home gives them a slight edge. Prediction: Rayo Vallecano 1-0 Getafe Best bet: Under 2.5 goals Celta Vigo vs Valencia Celta are usually strong at Balaídos, while Valencia remain inconsistent on the road. Expect a competitive game. Prediction: Celta Vigo 2-1 Valencia Best bet: Both teams to score Osasuna vs Athletic Club A fierce Basque clash. Athletic look the more complet

Cagliari vs Milan Milan enter as clear favourites, but trips to Sardinia are rarely comfortable. Cagliari will compete physically, though quality should prevail. Prediction: Cagliari 1-2 Milan Best bet: Milan to win Como vs Udinese Two sides hovering around the lower half. Udinese are more structured, while Como rely heavily on home energy. Prediction: Como 1-1 Udinese Best bet: Under 2.5 goals Sassuolo vs Parma An open matchup between two teams that prefer attacking foo

Burnley vs Newcastle United Turf Moor hosts a cagey-looking contest. Newcastle come in as clear favourites, but Burnley have ground out back-to-back draws and will hope to frustrate again. Prediction: Burnley 0-2 Newcastle Best bet: Woltemade to score & Newcastle to keep a clean sheet Chelsea vs Bournemouth Chelsea have struggled for consistency but should see this as a chance to reset. Bournemouth’s early-season momentum has faded badly, and they look vulnerable again. Pre

Clicking on the “Best Bet” text will redirect you to Midnite, where new customers can receive £30 in free bet credits when signing up. T&Cs apply. Parma vs Fiorentina Parma are competitive at home but Fiorentina’s structure and attacking quality should tilt the game in their favour. Prediction: Parma 1-2 Fiorentina Best bet: Fiorentina to win Torino vs Cagliari Torino are disciplined and usually strong at home, while Cagliari struggle to create chances away. Prediction: T

Clicking on the “Best Bet” text will redirect you to Bet365 , where new customers can receive £30 in free bet credits when signing up. T&Cs apply. Manchester United vs Newcastle United United, fresh off a loss against Aston Villa, host the Mapgies on Boxing Day in a legendary clash. Amorim will be banking on Old Trafford to solidify defensive issues, with Bruno likely to be out of the clash due to injury. Can the Red Devils hold a charging Newcastle? Prediction: Manchester U

Valencia vs Mallorca Valencia are disciplined at Mestalla and usually control games against mid-table opposition. Mallorca remain compact but limited going forward. Prediction: Valencia 2-0 Mallorca Best bet: Valencia to win & clean sheet Oviedo vs Celta Vigo Oviedo are competitive at home, but Celta’s experience and attacking quality give them the edge. Prediction: Oviedo 1-2 Celta Vigo Best bet: Celta Vigo to win Levante vs Real Sociedad Sociedad’s pressing and midfie

Borussia Dortmund vs Mönchengladbach Dortmund are usually dominant at Signal Iduna Park and play with much higher tempo. Gladbach can score, but their defence remains fragile. Prediction: Dortmund 3-1 Mönchengladbach Best bet: Dortmund to win & over 2.5 goals VfB Stuttgart vs Hoffenheim Stuttgart’s intensity and pressing at home should overwhelm Hoffenheim, who struggle defensively away. Prediction: Stuttgart 2-1 Hoffenheim Best bet: Stuttgart to win Wolfsburg vs SC Frei

Lazio vs Cremonese Lazio are strong at the Olimpico and usually control games against lower-half sides. Cremonese may sit deep but lack attacking threat. Prediction: Lazio 2-0 Cremonese Best bet: Lazio to win & clean sheet Juventus vs Roma A heavyweight clash. Juventus remain defensively solid at home, while Roma are dangerous on the counter but inconsistent away. Prediction: Juventus 1-1 Roma Best bet: Under 2.5 goals Cagliari vs Pisa Cagliari are physical and disciplin

Clicking on the “Best Bet” text will redirect you to Bet365 , where new customers can receive £30 in free bet credits when signing up. T&Cs apply. Newcastle vs Chelsea Newcastle host the Blues at St James’ Park for an early kickoff on Saturday. The Magpies will look to regain form after a loss to their bitter rivals Sunderland last macthweek. Expect a thrilling game. Prediction: Newcastle 1-2 Chelsea Best bet: Palmer to get a goal/assist + Cucurella to get fouled Wolves v