Serie A - Round 22 - Score Predictions & Best Bets

Inter vs Pisa

Inter welcome Pisa to San Siro knowing this is a must-win fixture as the title race tightens. Pisa have shown resilience this season but may struggle to cope with Inter’s intensity and attacking depth.

Prediction: Inter 3-0 Pisa

Best Bet: Inter win + Clean sheet

Como vs Torino

Como continue to impress on home soil, but Torino’s physicality and organisation could make this a tricky encounter. Expect a competitive, low-scoring affair.

Prediction: Como 1-1 Torino

Best Bet: Under 2.5 goals

Fiorentina vs Cagliari

Fiorentina will expect three points at home against a Cagliari side still flirting with the relegation zone. The Viola’s attacking quality should prove decisive.

Prediction: Fiorentina 2-0 Cagliari

Best Bet: Fiorentina win + Under 3.5 goals

Lecce vs Lazio

Lazio travel south looking to stay in the European places. Lecce will battle hard, but Lazio’s superior quality in midfield should swing the match their way.

Prediction: Lecce 1-2 Lazio

Best Bet: Lazio win or draw + BTTS

Sassuolo vs Cremonese

A relegation six-pointer that could have huge implications at the bottom. Both sides need points, which should open the game up more than usual.

Prediction: Sassuolo 2-1 Cremonese

Best Bet: BTTS

Atalanta vs Parma

Atalanta’s attacking style should overwhelm a Parma side that has struggled away from home. Expect goals and high tempo in Bergamo.

Prediction: Atalanta 3-1 Parma

Best Bet: Atalanta win + Over 2.5 goals

Genoa vs Bologna

Two well-organised sides meet in what could be one of the tightest games of the round. Chances may be at a premium.

Prediction: Genoa 1-1 Bologna

Best Bet: Under 2.5 goals

Juventus vs Napoli

The blockbuster of the weekend sees Juventus host Napoli in a clash that could shape the top-four race. Expect a tense, tactical battle between two heavyweights.

Prediction: Juventus 1-1 Napoli

Best Bet: Over 4 cards + Under 3.5 goals

Roma vs Milan

A classic Serie A showdown under the lights in Rome. Both sides have been inconsistent, but Milan’s attacking firepower could be the difference in an open contest.

Prediction: Roma 1-2 Milan

Best Bet: BTTS + Over 2.5 goals

Verona vs Udinese

Monday night football sees Verona host Udinese in a crucial lower-mid-table clash. Neither side can afford defeat, which may result in a cagey encounter.

Prediction: Verona 1-1 Udinese

Best Bet: Draw or Under 2.5 goals

Final Thoughts

Serie A Round 22 offers a strong mix of title pressure, European battles, and relegation dogfights. Juventus vs Napoli and Roma vs Milan headline the weekend, while Inter will look to keep the pressure on at the top with a comfortable home win.

Disclaimer: All Serie A predictions and betting tips are based on form analysis and available data. Football is unpredictable, always bet responsibly and make informed decisions.

Disclaimer: All Serie A predictions and betting tips are based on form analysis and available data. Football is unpredictable, always bet responsibly and make informed decisions.