Ajax vs Benfica The titans of their nations' domestic leagues, the two heavyweights will settle scores to decide who avoids last place in the UCL table. Ajax currently hold the title of the worst goal difference in the league, while Benfica are struggling to gain momentum under Jose Mourinho. Prediction: Ajax 1-2 Benfica Best Bet: Benfica to score first + Over 2 cards Dortmund vs Villareal The Yellow Submarines travel to the Signal Iduna Park to take on the fierce Yellow Wal

Burnley vs Chelsea A clash at opposite ends of the table, Chelsea seek to continue their strong form against an unpredictable Burnley side, who could cause trouble at Turf Moor. Prediction: Burnley 1-3 Chelsea Best Bet: Chelsea to win + over 2.5 goals Bournemouth vs West Ham Bournemouth star Semenyo will look to reinvigorate a side that has struggled in recent weeks, as they face a struggling West Ham side looking to avoid relegation. Prediction: Bournemouth 2-0 West Ham B

Nice vs Marseille A heated southern derby. Nice are tough to beat at home, while Marseille can look dangerous but inconsistent on the road. Expect a tight battle. Prediction: Nice 1-1 Marseille Best bet: Both teams to score Lens vs Strasbourg Lens at home typically play with intensity and press high. Strasbourg can frustrate but struggle in transition against stronger sides. Prediction: Lens 2-0 Strasbourg Best bet: Lens to win & clean sheet Rennes vs Monaco Rennes at Roa

1. FC Heidenheim vs Borussia Mönchengladbach Heidenheim are tough at home but vulnerable to pace. Gladbach need to rediscover sharpness. Prediction: Heidenheim 1-2 Gladbach Best bet: Gladbach to win & both teams to score Bayern München vs SC Freiburg Bayern at home should dominate; Freiburg organised but may concede given Bayern’s attacking fire-power. Prediction: Bayern München 3-1 SC Freiburg Best bet: Bayern to win & over 2.5 goals Borussia Dortmund vs VfB Stuttgart